2 mpf 2 mpf 2 mpf 2 mpf 2 mpf 6 mpf 6 mpf 6 mpf 12 mpf 12 mpf 12 mpf 12 mpf 12 mpf WT 0 0 0 0 0 0.1 0 0.2 0.9 0.2 0.3 0.3 DKO 1.6 1.3 0 0.5 5.3 6.4 4.8 8 12.3 17.7 19.7 10.7 prg4a-/- 7.3 0.8 0 prg4b-/- 19.6 10.4 13.6