kappa = 3.04178
omega = 0.517813
phi0A = 0.342506
phi0C = 0.148721
phi0G = 0.255705
phi1A = 0.339504
phi1C = 0.182867
phi1G = 0.210549
phi2A = 0.425231
phi2C = 0.14709
phi2G = 0.193441