mmHg Vehicle (V) PRS +Vehicle (PRS V) PRS +NCDO2118 + glutamate (LG) PRS NCDO 2727 + glutamate (2727G) 0 12 2 0 0 2 7 1 0 2 4 3 0 0 0 10 0 0 2 3 0 3 6 6 6 7 2 15 13 9 13 9 8 0 3 0 8 2 0 15 13 0 6 10 5 5 1 0 0 12 8 10 18 0 7 9 0 2 11 1 18 16 23 4 0 1 11 10 6 3 46 8 2 8 2 27 7 0 30 12 13 11 27 15 9 19 5 11 18 33 34 41 37 45 29 24 36 24 10 18 30 28 19 37 18 16 7 32 17 54 53 30 37 18 56 59 5 45 20 14 11 37 39 17 28 30 11 18 60 45 63 72 54 51 56 56 25 44 30 32 42 53 49 36 14 42 19 57 61 55 60 33 63 55 16 60 24 18 16 37 46 23 38 53 19 48 66 43 68 74 87 52 88 59 49 63 28 44 46 43 48 37 38 11 49 20 61 61 55 76 39 81 57 29 FIGURE 2B Source data