mmHg Vehicle (V) PRS + Vehicle (PRS V) PRS +NCDO2118 + glutamate (PRS LG) PRS +NCDO 2118 +glu + antago 3mg/kg (PRS LGA) 0 5 0 4 2 2 1 0 2 2 5 0 9 8 3 4 1 0 8 17 4 3 0 3 6 6 6 7 2 15 13 9 13 9 3 4 0 1 4 6 0* 15 9 0 7 6 7 1 0 7 15 7 5 16 15 17 5 4 5 5 31 4 11 1 18 16 23 4 0 1 11 10 6 3 17 17 1 8 2 5 14 0* 30 31 9 21 10 24 11 18 14 16 10 57 33 37 34 28 8 50 43 70 16 24 10 18 30 28 19 37 18 16 7 32 17 47 35 33 43 38 20 34 30* 45 42 26 39 22 25 24 32 18 32 14 64 40 40 30 47 30 55 44 83 39 25 44 30 32 42 53 49 36 14 42 19 54 42 48 53 40 47 43 26* 60 44 28 38 36 37 27 25 27 58 14 63 41 38 50 55 48 74 60 86 42 49 63 28 44 46 43 48 37 38 11 49 20 54 52 50 67 45 48 47 24* FIGURE 3B Source data